FIELD: chemistry; biochemistry.
SUBSTANCE: invention relates to molecular biology and gene therapy. disclosed is a group siNA (siRNA) aimed at certain gene areas of the P2X7 (P2RX7) receptor and which efficiently inhibit expression of said receptor.
EFFECT: invention discloses use of siRNA directly, as well as a component of medicinal agents for treating diseases characterised by high expression and/or activity of the P2X7 receptor such as neural degeneration, Alzheimer disease, inflammatory diseases, certain types of malignant tumours etc.
26 cl, 5 dwg, 3 ex
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