FIELD: medicine.
SUBSTANCE: invention refers to biotechnology, and represents an application of siRNA able to inhibit 11 beta-steroid dehydrogenase 1 (11beta-HSDl) expression for preparing a drug for treating an eye disease characterised by intraocular pressure (IOP) variations. Also, a method of treating such eye disease, as well as a recovered siRNA compound able to inhibit 11beta-HSDl expression, are presented.
EFFECT: invention can be used in treating the eye disease characterised by intraocular pressure variations.
21 cl, 10 dwg, 1 ex
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