MEDICATION FOR PHOTODYNAMIC THERAPY, METHOD OF OBTAINING CLAIMED MEDICATION AND METHOD OF CARRYING OUT PHOTODYNAMIC THERAPY WITH APPLICATION OF CLAIMED MEDICATION Russian patent published in 2011 - IPC A61K31/409 A61K47/44 A61K47/26 A61K47/12 A61K9/127 A61P35/00 A61N5/67 

FIELD: medicine.

SUBSTANCE: medication for photodynamic therapy (PDT) includes photosensitising substance based on hydrophilic chlorine E6 derivative, phosphatidylcholine, cholesterol, citric acid and saccharose with definite molar component ratio. Method of obtaining said medication includes dissolution of phosphatidylcholine and cholesterol in chloroform, mixing said solutions and further evaporation under vacuum until formation of film, which is dispersed with water solution of chlorine E6 derivative into liposomal dispersion. After that, into liposomal dispersion water solution of saccharose and citric acid with pH 5.0 is added and lyophilised, and immediately before intravenous introduction redispersed with application of distilled water or physiological solution. Method of carrying out PDT lies in systemic introduction of claimed medication and irradiation of pathologic section 4-5 hours after its introduction with optic irradiation, absorbed by chlorine E6. Claimed method of obtaining medication for PDT ensured increase of chlorine E6 derivative inclusion into said medication, increase of its stability in long storage and increase of its technological output.

EFFECT: high efficiency of photodynamic therapy and selectiveness of accumulation.

3 cl, 4 dwg, 3 ex