4-[(3-FLUOROPHENOXY)PHENYLMETHYL]PIPERIDINE METHANESULPHONATE: USE, SYNTHESIS METHOD AND PHARMACEUTICAL COMPOSITIONS Russian patent published in 2011 - IPC C07D211/22 A61K31/4465 A61P25/00 

Abstract RU 2412169 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a novel salt of methanesulphonic acid 4-[(3-fluorophenoxy)phenylmethyl]piperdine of formula I

,

anantiomers thereof or mixtures thereof. The invention also relates to a salt of methanesulphonic acid (S)-4-[(3-fluorophenoxy)phenylmethyl]piperdine, a salt of methanesulphonic acid (R)-4-[(3-fluorophenoxy)phenylmethyl]piperdine, a method of producing said compounds which are defined in any of the claims 1-4, a pharmaceutical composition, as well as to use of compounds defined in any of the claims 1-4.

EFFECT: obtaining novel biologically active compounds having norepinephrine and serotonin reuptake selective inhibitory activity.

11 cl, 10 ex, 1 tbl

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RU 2 412 169 C2

Authors

Orkhales Venero Aurelio

Moskera Pestan'Ja Ramon

Pumar Duran Marija Karmen

Toledo Avel'O Antonio

Kanal Mori Gonsalo

Bordel' Martin Maravil'Jas

Dates

2011-02-20Published

2007-04-12Filed