COMPOUND FOR USE IN TREATING NEUROGENIC ORTHOSTATIC HYPOTENSION Russian patent published in 2020 - IPC A61K31/165 A61K31/192 A61K31/4465 A61K31/573 A61K45/06 A61P9/02 

FIELD: medicine.

SUBSTANCE: group of inventions refers to internal diseases, and aims at treating neurogenic orthostatic hypotension and its symptoms in a human patient. Method of treating said hypotension and its symptoms in a human patient comprises administering to a patient a compound of formula I or a pharmaceutical composition, containing a pharmaceutically acceptable carrier and a compound of formula I:

or its pharmaceutically acceptable salt once a day in amount of 1 mg/day to 20 mg/day. Patient has multiple systemic atrophy, true autonomic insufficiency or Parkinson's disease.

EFFECT: administering a compound or pharmaceutical composition to a patient results in one or more of: (a) increasing systolic blood pressure in a patient in a sitting position, (b) longer patient staying in a standing position and (c) less faintness or a feeling of a pre-patch condition experienced by the patient.

20 cl, 7 tbl, 16 ex