CRYSTALLINE FORM OF 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUND Russian patent published in 2014 - IPC C07D211/22 A61K31/4409 A61P25/00 

Abstract RU 2503662 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a crystalline form of 4-[2-(2,4,6-trifluorophenoxymethyl)phenyl]piperidine hydrochloride which is characterised by an X-ray powder diffraction profile having diffraction peaks at the following values of 2Θ: 4.44±0.20, 10.22±0.20, 17.16±0.20 and 21.78±0.20. The present invention also relates to a pharmaceutical composition containing a crystalline form of 4-[2-(2,4,6-trifluorophenoxymethyl)phenyl]piperidine hydrochloride and having norepinephrine and serotonin reuptake inhibitor action, methods of producing said crystalline salt and use of the crystalline salt to treat diseases, e.g., pain syndrome etc.

EFFECT: novel crystalline form of a compound which can be used in treating a range of diseases is obtained and described.

11 cl, 8 ex, 5 dwg

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RU 2 503 662 C2

Authors

Patterson Lori Dzhin

Chao Robert

Rapta Miroslav

Dates

2014-01-10Published

2009-11-13Filed