NEW DERIVATIVES OF PIPERIDINE AND THEIR USE AS INHIBITORS OF RECAPTURE OF NEUROMEDIATOR MONOAMINES Russian patent published in 2008 - IPC C07D211/22 C07D211/60 A61K31/445 A61K31/451 A61P25/00 

FIELD: chemistry.

SUBSTANCE: invention relates to new derivatives of piperidine of the formula I: or to any of its isomers, or to any mixture of its isomers, or to its pharmaceutically acceptable salt, where R¹ is a hydrogen or alkyl, R³ is -CH₂-O-R^c; where R^c is alkyl or cycloalkylalkyl; R⁴ is , where R^a and R^b act, independently, as halogens. The invention relates also to pharmaceutical composition and to use compounds based on formula I, that feature inhibiting activity of recapture of neuromediator monoamines in central nervous system. EFFECT: production of new biologically active compounds and pharmaceutical compositions on their base.

10 cl, 5 ex, 1 tbl