FIELD: medicine.
SUBSTANCE: antagonistic activity of lactobacterium and/or bifidobacterium is determined simultaneously by method of double-layer agar and method of inverted agar, inoculation being performed by Gold. Power of antagonistic impact of probiotic strains of opportunistic microorganisms (OM) in comparison with control is estimated by degree of strain inhibition intensity. Antagonistic activity of probiotics is detected by one or two of said methods. In case of individual detection of antagonistic activity of probiotic medications, containing lactobacteria, in case of absence of antagonistic activity or detection of low or medium degree of intensity of OM inhibition, antagonistic activity is additionally detected by drop method.
EFFECT: increase of method accuracy and extension of spectrum of optimally selected probiotic medications for particular patient, simplification of inoculation and account of obtained result.
2 cl,3 dwg, 10 tbl
