METHOD FOR DETERMINING SEVERITY LEVEL OF ACUTE PANCREATITIS Russian patent published in 2011 - IPC A61B10/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, and can be used for determining a severity level of acute pancreatitis. That is ensured by patient's lymphocyte chemoluminescence and measuring a production level of active forms of oxygen. Spontaneous chemoluminescence Imax within 46.12 to 266.12, Squar within 2.5E+05 to 7.8E+04, Tmax within 3.2 to 4.5, Tcent within 9.2 to 17.4, Simtr within 2.6E-01 to 5. OE-01 and activated chemoluminescence Imax within 48.0 to 151.0, Squar within 1.2E+05 to 3.9E+05, Tmax within 4.3 to 8.4, Tcent within 27.7 to 30.3, Simtr within 1.7E-01 to 2.8E-01 show a mild severity of acute pancreatitis. Herein, Imax is chemoluminescence intensity, Squar is a curve area, Tmax is peaking time, Tcent is percent peaking time, Simtr is curve symmetry, E is estimated chemoluminescence activity described by kinetic parametres of the chemoluminescence reaction curves. In case of Imax> 266.2, Squar≤2.4E+05, Tmax> 4.6, Tcent≤9.1, Simtr> 5.1E-01 and activated Imax> 151.1, Squar> 4.0E+05, Tmax> 8.5, Tcent> 30.4, Simtr> 2.9E-01, the severity level is considered to be moderate. Spontaneous Imax≤46.0, Squar> 7.9E+04, Tmax≤3.1, Tcent> 17.5, Simtr≤2.5E-01 and activated Imax≤47.9, Squar≤1.1E+05, Tmax≤4.2, Tcent≤27.6, Simtr≤1.6E-01 indicate the severe disease.

EFFECT: method allows higher objectivity and fast determination of the severity of a pathological process and prescription of enhanced antibacterial and detoxification therapy in cases of the severe disease.

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