FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine, namely to dentistry. Offered is a method of mineralising a dental enamel involving contacting the dental enamel or a dental damage with a protein-solubilising, protein-destroying or protein-hydrolysing agent preceding contacting the dental enamel with phosphopeptide-stabilised amorphous calcium phosphate (ACP) or amorphous calcium fluoride phosphate (ACFP). Preferentially, phosphopeptide is casein phosphopeptide (CPP). The protein-solubilising, protein-destroying or protein-hydrolysing agent is chosen from one or more substances of the group consisting of a bleaching agent, a detergent, a chaotropic agent, protease or mixed proteases. Preferentially, the bleaching agent such as sodium hypochlorite or carbamide peroxide is used. Also, offered are methods of mineralising hypomineralised dental enamel damages caused by caries, fluorosis, dental erosion and a therapeutic kit for treatment and prevention of said conditions, including: a) the protein-solubilising, protein-destroying or protein-hydrolysing agent and b) a CPP-ACP or CPP-ACFP complex in a pharmaceutically acceptable carrier.
EFFECT: attained effective reconditioning of a missing mineral in the dental enamel with hypomineralised damages.
10 cl, 2 tbl
