3,5-SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS Russian patent published in 2011 - IPC C07D211/60 C07D401/12 C07D401/14 C07D405/12 C07D405/14 C07D409/12 C07D413/12 C07D413/14 C07D471/04 A61K31/445 A61K31/4525 A61K31/453 A61K31/4535 A61K31/454 A61K31/4545 A61P9/12 

Abstract RU 2415840 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: there are described 3,4-substituted piperidines applicable in diagnostics and drug therapy of a warm-blooded animal, preferentially for therapy of a disease which depends on renin activity; application of a compound of such kind for preparing a pharmaceutical composition for therapy of the disease which depends on renin activity; application of the compound of such kind for therapy of the disease which depends on renin activity; the pharmaceutical compositions containing 3,4-substituted piperidine, and/or a therapeutic mode involving administration of 3,4-substituted piperidine, a method for producing 3,4-substituted piperidine. The preferential compound (which also can be presented in the form of salts) are described by formula I' wherein R1, R2, T, R3 and R4 are such as described by the patent claim.

EFFECT: production of the compounds for therapy of the disease which depends on renin activity.

28 cl, 1 tbl, 375 ex

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RU 2 415 840 C2

Authors

Ehkhara Takeru

Groshe Filipp

Irie Osamu

Ivaki Juki

Kanazava Takanori

Kavakami Shimpej

Konishi Kazukhide

Mogi Muneto

Suzuki Masaki

Jokokava Fumiaki

Dates

2011-04-10Published

2006-12-28Filed