FIELD: medicine, pharmaceutics.
SUBSTANCE: there are described 3,4-substituted piperidines applicable in diagnostics and drug therapy of a warm-blooded animal, preferentially for therapy of a disease which depends on renin activity; application of a compound of such kind for preparing a pharmaceutical composition for therapy of the disease which depends on renin activity; application of the compound of such kind for therapy of the disease which depends on renin activity; the pharmaceutical compositions containing 3,4-substituted piperidine, and/or a therapeutic mode involving administration of 3,4-substituted piperidine, a method for producing 3,4-substituted piperidine. The preferential compound (which also can be presented in the form of salts) are described by formula I' wherein R1, R2, T, R3 and R4 are such as described by the patent claim.
EFFECT: production of the compounds for therapy of the disease which depends on renin activity.
28 cl, 1 tbl, 375 ex
Title | Year | Author | Number |
---|---|---|---|
PHENYL DERIVATIVES AS PPAR AGONISTS | 2004 |
|
RU2374230C2 |
ORGANIC COMPOUNDS | 2005 |
|
RU2411239C2 |
METHOD OF PRODUCTION OF MEVALONIC ACID DERIVATIVES INHIBITING HMG-COA REDUCTASE | 2003 |
|
RU2335500C2 |
(-AMINO-(-HYDROXY-(-ARYLALKANOIC AMIDES AND USE THEREOF AS RENIN INHIBITORS | 2004 |
|
RU2425027C2 |
COUMARONE DERIVATIVES ELICITING COMT-INHIBITING ACTIVITY | 2001 |
|
RU2282627C2 |
PHOSPHINIC ACID DERIVATIVES, BETA-SECRETASE INHIBITORS FOR TREATING ALZHEIMER'S DISEASE | 2004 |
|
RU2367666C2 |
1,3-DIOXO-2,3-DIHYDRO-1H-PYRROLO[3,4-C]QUINOLINES (VARIANTS), PHARMACEUTICAL COMPOSITIONS (VARIANTS), METHOD FOR THEIR PREPARING (VARIANTS) AND METHOD FOR TREATMENT (VARIANTS) | 2003 |
|
RU2257385C2 |
PHARMACEUTICAL COMBINATIONS CONTAINING PYRIDO[4,3-d]PYRIMIDINE DERIVATIVES AS HSP90 INHIBITOR AND HER2 INHIBITOR | 2009 |
|
RU2532375C2 |
SPIROCYCLIC CYCLOHEXANE DERIVATIVES | 2003 |
|
RU2354656C2 |
SUBSTITUTED 2,3,4,5-TETRAHYDRO-1N-PYRIDO[4,3-b]INDOLES, METHOD OF OBTAINING THEM AND USE | 2007 |
|
RU2338745C1 |
Authors
Dates
2011-04-10—Published
2006-12-28—Filed