METHOD OF OBTAINING 4-NITROIMIDAZOLE COMPOUND Russian patent published in 2009 - IPC C07D233/92

Abstract RU 2345071 C2

FIELD: chemistry, pharmaceutics.

SUBSTANCE: invention relates to method of obtaining compound of 4-nitroimidazole, represented by general formula (1): , where X represents chlorine atom or bromine atom, including iodinating of 4-niotroimidazole compound represented by general formula (2): , where each of X¹ and X² represents chlorine atom or bromine atom, with further reduction of obtained compound of 5-iodine-4-nitroimidazole, represented by general formula (3): , where X has value determined above. Compounds of 4-nitroimidazole, represented by general formula (1), are useful intermediate compounds used for obtaining anti-tuberculosis medications.

EFFECT: obtaining compounds of general formula (I), with high output and high purity, by explosion-safe method.

1 cl, 1 tbl, 20 ex

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RU 2 345 071 C2

Authors

Sinkhama Koiti

Dates

2009-01-27—Published

2005-02-15—Filed