SOLVATING SYSTEM AND HERMETIC FOR MEDICAL APPLICATION Russian patent published in 2011 - IPC A61K9/00 A61K45/08 A61K31/205 A61K33/00 C09J9/00 A61P31/00 A61P31/04 

FIELD: medicine.

SUBSTANCE: claimed is application of: (a) solvating system which contains surface active substance, able to separate, remove or destruct in any other way, at least, part of biofilm, attached or adhered to a part of middle or internal ear, to the surface in nasal cavity or in sinus cavity, or to mouth or gullet tissue, and (b) polymer film-forming medical hermetic, able to form protective layer above the place, on which such biofilm was destroyed, and which possesses adhesion to natural tissues in the processed place and is resistant to separation or other destruction until natural decomposition or resorption of hermetic takes place, for manufacturing therapeutic system for treatment of infectious diseases of ear or throat, corresponding method of treatment and composition of said hermetic and anti-microbial preparation, which includes gallium-containing compound for application in the method. Demonstrated is 5.2-fold logarithmic reduction of the level of microbial contamination in vitro by cultures Staphylococcus aureus, Pseudomonas aeruginosa.

EFFECT: invention suggests efficiency of treatment by the claimed method of chronic otitis media with evaporation (COME), recurrent acute otitis media (RAOM), cholesteatoma, chronic rhinosinusitis.

71 cl, 4 dwg, 2 ex, 1 tbl