FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed invention relates to hydrosulphate salt of compound 1 
its solvates, crystalline forms and amorphous forms, as well as to method of obtaining them. In addition, invention relates to application of claimed salt in manufacturing of medication for treatment of MEK-mediated disease states and to methods of said state treatment.
EFFECT: elaboration of efficient method of obtaining hydrosulphate salt of compound.
16 cl, 3 ex, 3 tbl, 3 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| HETEROCYCLIC MEK INHIBITORS AND METHODS OF USING THEREOF | 2006 |
|
RU2414455C2 |
| PHARMACEUTICAL COMPOSITION 271 | 2009 |
|
RU2491920C2 |
| N3-ALKYLATED BENZIMIDAZOLE DERIVATIVES AS MEK INHIBITORS | 2003 |
|
RU2300528C2 |
| COMBINATION THERAPY | 2013 |
|
RU2677245C2 |
| AZABENZOTHIOPHENYL COMPOUNDS AND METHODS OF USE | 2007 |
|
RU2444524C2 |
| AURORA AND FLT3 KINASES MODULATORS | 2013 |
|
RU2643809C2 |
| PROPOSED 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS | 2022 |
|
RU2826000C1 |
| NOVEL 2,4-DIAMINOTHIAZOL-5-ONE DERIVATIVES | 2005 |
|
RU2395501C2 |
| AZAINDOLIZINES AND METHODS FOR PREPARING THEM | 2008 |
|
RU2483069C2 |
| BIPHENYLOXYACETIC ACID DERIVATIVES, USE THEREOF IN PREPARING MEDICINAL AGENT AND INTERMEDIATE COMPOUNDS | 2006 |
|
RU2424229C2 |
