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(19)

(11)

2 683 940

(13)

(51)

IPC

C07D513/04(2006-01-01)

A61K31/4188(2006-01-01)

A61P29/00(2006-01-01)

(21) (22)

Application

2016127226, 2014-12-08

(24)

Start date

2014-12-08

(22)

Actual filing date

2014-12-08

(45)

Published

2019-04-03

(72)

Inventor

Aleksander Rikki PiterAli Mezkher KhussejnBraun Dzhulien AlisterDzhekson Viktoriya Elizabet

(73)

Holder

Ucb Biopharma Sprl

IMIDAZOTHIAZOLE DERIVATIVES AS TNF ACTIVITY MODULATORS Russian patent published in 2019 - IPC C07D513/04 A61K31/4188 A61P29/00

Abstract RU 2683940 C1

FIELD: pharmaceutical industry.

SUBSTANCE: invention relates to a compound which is 5-[(2,5-dimethylphenyl)methyl]-6-methyl-2-(1-methylpyrazol-4-yl)imidazo[2,1-b]-thiazole. Invention also relates to a pharmaceutical composition having the properties of a TNFα activity modulator, containing an effective amount of 5-[(2,5-dimethylphenyl)methyl]-6-methyl-2-(1-methylpyrazol-4-yl)imidazo[2,1-b]-thiazole with a pharmaceutically acceptable carrier.

EFFECT: disclosed compound is applicable for treating and/or preventing rheumatoid arthritis or Crohn's disease.

4 cl, 2 ex

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RU 2 683 940 C1

Authors

Aleksander Rikki Piter

Ali Mezkher Khussejn

Braun Dzhulien Alister

Dzhekson Viktoriya Elizabet

Dates

2019-04-03—Published

2014-12-08—Filed