FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutical industry. A liquid pharmaceutical composition containing cyclosporine, an aqueous liquid carrier, a first solubility-enabling substance selected from a group of phospholipids and a second solubility-enabling substance selected from a group of non-ionic surface-active substances, and a phospholipid represents a mixture of natural phospholipids and contains cyclosporine in a liposomally solubilised form. A method of producing the composition. Application of the composition. A container containing the composition. A method of filling the container with the composition. Method of producing an aerosol.
EFFECT: composition described above is stable and effective for oral, parenteral, nasal, topical, mucosal introduction, and especially for aerosolised introduction in lungs.
50 cl, 3 dwg, 13 ex
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Authors
Dates
2011-06-20—Published
2006-11-29—Filed