FIELD: medicine.
SUBSTANCE: stable inheritance effect is independent of an insertion position and orientation. The introduction of said sequence essentially reduces the loss frequency of both low-copy, and high-copy vectors. The given invention can find application in plasmid-bearing strain selection. And the cultivation of said strains does not require a selective medium to be used.
EFFECT: higher stability of vector inheritance.
1 dwg, 1 tbl, 3 ex
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