FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to new compounds of general formula ii-d and to their pharmaceutically acceptable salts. In formula ii-d: 
, R2 represents C1-3-alkyl or cyclopropyl; R5 represents CH2CH3, CH2CF3, CH2CH2CF3, 
or 
Ry represents 
or 
Jl represents hydrogen atom or CH3J2 represents C1-4-alkyl; and Cy represents C3-5-cycloalkyl.
EFFECT: production of new compounds of general formula ii-d and their pharmaceutically acceptable salts which exhibit properties of an Aurora-protein kinase activity inhibitor and can be used in treating proliferative disorders.
12 cl, 8 tbl, 19 ex
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|---|---|---|---|
| AMINOPYRIMIDINES AS KINASE INHIBITORS | 2006 |
|
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|
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RU2423351C2 |
