METHOD OF RECOVERING VIABILITY OF ISCHEMICALLY AFFECTED DONOR ORGANS Russian patent published in 2011 - IPC A61B17/00 A61K31/02 A61K31/727 A61K31/573 A61K33/14 A61K38/49 A61P41/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to transplantology, and can be used in realisation of donor organs preservation. For this purpose from the region of supposed explantation of donor organ, blood is evacuated with its further cooling, oxygenation and returning into bloodstream, providing perfusion of said region. After that, removal of donor organ is performed and during not less than two hours its extracorporal perfusion with prepared perfusion solution is carried out. Composition of perfusion solution includes not less than 25% of preserving solution "Kustodiol", not less than 20% of perfluorane, not less than 1.5 mln IU of streptokinase, not less than 50000 IU of heparin, not less than 300 mcg of prednisolone. After organ removal activated leukocytes are removed from contour of extracorporal apparatus perfusion by means of leukocyte filter, and temperature of perfusion solution is reduced to 5°C-12°C.

EFFECT: method makes it possible to ensure extension of donor pool as a result of possible use of ischemically affected donor organs due to restoration of energy and functional potential of cells, including as a result of application of perfusion solution of multi-directional action.

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