METHOD OF EXTRACORPORAL RECOVERY OF PERFUSION AND OXYGENATION IN DONOR BODY Russian patent published in 2018 - IPC A61M1/10 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely, transplantology, and can be used in the extracorporeal restoration of perfusion and oxygenation within the body of the donor. To do this, after carrying out a complex of resuscitation measures and ascertaining the biological death of a patient, at least 25,000 units of heparin are injected into the subclavian catheter and indirect heart massage is performed. Before the perfusion, which is carried out using a centrifugal pump, up to four liters of perfusion solution is introduced into the system of the inferior vena cava. After the centrifuge pump is turned on, the perfusion rate is gradually increased from 1 to 5 l/min and the pressure at the entrance to the arterial cannula and at the exit from the venous cannula is controlled, the mean value of which in the perfusion loop is maintained at 90 mm Hg. If this pressure is exceeded, the rate of perfusion is reduced. With a decrease in pressure at the exit from the venous cannula, less than 10 mm Hg at least 500 ml of perfusion solution is injected into the perfusion circuit. Perfusion is performed at a temperature of 23–27 °C, with the withdrawal of donor organs on ongoing perfusion.

EFFECT: method ensures high quality of transplants from donors with damaged organs due to effective restoration and maintaining the viability of damaged donor organs due to the resumption of blood flow in the donor's vessels with oxygenation and leukocyte purification of the perfusion solution circulating in the perfusion loop.

1 cl, 1 dwg