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2 581 919

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IPC

A61K31/7068(2006-01-01)

A61K31/407(2006-01-01)

A61K31/337(2006-01-01)

A61P35/00(2006-01-01)

A61N5/10(2006-01-01)

(21) (22)

Application

2015104733/15, 2015-02-12

(24)

Start date

2015-02-12

(22)

Actual filing date

2015-02-12

(45)

Published

2016-04-20

(72)

Inventor

Rasulov Arsen OsmanovichGorbunova Vera AndreevnaTkachev Sergej IvanovichGordeev Sergej SergeevichBesova Natalja SergeevnaFedjanin Mikhail JurevichGlebovskaja Valerija VladimirovnaKuzmichev Dmitrij Vladimirovich

(73)

Holder

Federalnoe Gosudarstvennoe Bjudzhetnoe Nauchnoe Uchrezhdenie Onkologicheskij Nauchnyj Tsentr Imeni N.N. Blokhina" Im. N.N. Blokhina")

METHOD OF TREATING SQUAMOUS CELL CANCER OF ANAL CANAL Russian patent published in 2016 - IPC A61K31/7068 A61K31/407 A61K31/337 A61P35/00 A61N5/10

Abstract RU 2581919 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, specifically to oncology, and can be used in treating squamous cell cancer of anal canal. Method involves exposure of tumour to radiation teletherapy in a single basic dose 2 Gy, total radiation dose 50-56 Gy for 35-40 days, 5 times a week combined with chemotherapy mitomycin C in dosage of 10 mg/m² on first day of treatment intravenously, with capecitabine. Capecitabine is used in dose of 650 mg/m²2 times a day on days of radiation therapy orally, and paclitaxel is added in dose of 45 mg/m² 1 time a week for 5 weeks intravenously.

EFFECT: using invention enables complete tumour regression in 91 7/10 % patients with squamous cell cancer of anal canal with predominance of common T3-T4 steps and/or involvement of regional lymph nodes without application of surgical treatment.

1 cl, 2 ex

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RU 2 581 919 C1

Authors

Rasulov Arsen Osmanovich

Gorbunova Vera Andreevna

Tkachev Sergej Ivanovich

Gordeev Sergej Sergeevich

Besova Natalja Sergeevna

Fedjanin Mikhail Jurevich

Glebovskaja Valerija Vladimirovna

Kuzmichev Dmitrij Vladimirovich

Dates

2016-04-20—Published

2015-02-12—Filed