FIELD: chemistry.
SUBSTANCE: invention relates to novel 3,4-dihydrobenzoxazine compounds of general formula 
[1] (where X denotes a nitrogen atom or CR3; R1 denotes a hydrogen atom or a halogen atom; R2 denotes a C1-6alkoxy group which can be substituted with 1-5 identical or different substitutes selected from a halogen atom and a hydroxyl group; and R3 denotes a halogen atom. However, R1 denotes a halogen atom when X denotes CR3). Said compounds are effective when treating diseases where activity of vanilloid receptors subtype 1 (VR1) is involved, e.g. pain.
EFFECT: more efficient use of pharmaceutical compositions based on said compounds, more effective treatment or pain killing.
19 cl, 4 tbl, 10 ex
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| CONDENSED BENZAMIDE DERIVATIVE AND INHIBITOR OF VANILLOID RECEPTOR TYPE 1 ACTIVITY (VRI) | 2005 |
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