FIELD: chemistry.
SUBSTANCE: invention relates to a tosylate salt of trans-N-ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)-phenyl]-cyclobutane carboxamide of formula 
The invention also relates to a pharmaceutical composition, as well as a treatment method.
EFFECT: obtaining a novel biologically active salt of a compound, having activity on histamine receptor type 3.
11 cl, 1 ex, 1 tbl, 3 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| TOSYLATE SALT OF TRANS-N-ISOBUTYL-3-FLUORO-3-[3-FLUORO-4-(PYRROLIDIN-1-YLMETHYL)PHENYL]CYCLOBUTANE CARBOXAMIDE | 2008 |
|
RU2451016C2 |
| SUBSTITUTED N-PHENYLPYRROLIDINYL METHYLPYRROLIDINE AMIDES AND THERAPEUTIC USE THEREOF AS MODULATORS OF HISTAMINE H3 RECEPTOR | 2008 |
|
RU2477721C2 |
| NOVEL SALT FORM OF DOPAMINE AGONIST | 2006 |
|
RU2393153C2 |
| THERAPEUTIC AGENTS 713 | 2010 |
|
RU2526055C2 |
| POLYMORPHOUS AND AMORPHOUS FORMS OF 8-FLUORO-2-{4-[(METHYLAMINO)METHYL]PHENYL}-1,3,4,5-TETRAHYDRO-6H-AZEPINE[5,4,3-CD]INDOL-6-ON PHOSPHATE | 2005 |
|
RU2355691C2 |
| NAPADISYLATE SALT OF MUSCARINIC M3 RECEPTOR ANTAGONIST | 2008 |
|
RU2459810C2 |
| TOSYLATE SALT OF 5-PYRAZOLYL-2-PYRIDONE DERIVATIVE EFFECTIVE IN COPD TREATMENT | 2010 |
|
RU2526038C2 |
| SUCCINATE 2-((4-(1-METHYL-4-(PYRIDIN-4-YL)-1H-PYRAZOL-3-YL)PHENOXY)METHYL)QUINOLINE SALT | 2007 |
|
RU2430918C2 |
| 3-SUBSTITUTED PYRIDINE DERIVATIVES AS HISTAMINE H3 RECEPTOR ANTAGONISTS | 2005 |
|
RU2389721C2 |
| COMPOSITIONS AND METHODS FOR TREATING COGNITIVE DISORDERS | 2005 |
|
RU2420318C2 |
