METHOD OF PREDICTING RISK OF DEVELOPMENT OF COMPLICATIONS IN PATIENTS WITH TRAUMA OF PELVIC BONES Russian patent published in 2011 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: on 5-7 day after pelvis trauma blood serum is analysed and concentration of polypeptides of type 1 collagen (CICP, ng/ml), concentration of osteotropic cytokine - osteprotegerin (OPG, pmol/k) and prothrombin by Quick (%) are determined. Values of prothrombin by Quick and OPG concentration are used to calculate value of discriminant function: F(Y₁, Y₂) = 0.170767466 · Y₁ - 2.15811515 · Y₂ - 13.11227538 (1) where Y₁ is prothrombin value bu Quick, %, Y₂ is Ln (natural logarithm) of OPG concentration in blood serum, pmol/l. If CICP value constitutes less than 146 ng/ml, and value F>0, absence of complications in post-operation period is predicted. If CICP value is higher than 146 ng/ml, and value F<0, patient is referred to group of risk on development of complications in post-operation period.

EFFECT: application of method makes it possible to predict risk of developing complications of traumatic disease course in post-operation period before surgery.

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