METHOD OF PREDICTING PREGNANCY IN PROGRAMME OF EXTRACORPORAL FERTILISATION AND TRANSFER OF EMBRYOS IN STANDARD LONG PROTOCOL OF SUPEROVULATION STIMULATION Russian patent published in 2011 - IPC G01N33/74 

Abstract RU 2430379 C1

FIELD: medicine.

SUBSTANCE: before programme of ECF and TE in standard long protocol of superovulation stimulation in patient analysis of hormonal status is performed - content of progesterone receptors in mononuclear fraction of peripheral blood cells is determined. Content of progesterone receptors in mononuclear fraction of peripheral blood cells is determined in the middle of luteal phase of patient's menstrual cycle, before administration of gonadotropin-releasing hormone agonist when carrying out treatment in accordance with standard long protocol of superovulation stimulation. If value is more than 700 progesterone receptors per cell, pregnancy as a result of programme of ECF and TE in standard long protocol of superovulation stimulation is predicted.

EFFECT: method ensures analysis simplicity, reduction of its cost, increase of prediction reliability due to taking into account of objective index, indirectly characterising patients' endometrium hormonal status, by determination of progesterone receptors level in mononuclear fraction of peripheral blood cells before beginning treatment.

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RU 2 430 379 C1

Authors

Savel'Eva Galina Mikhajlovna

Shimanovskij Nikolaj L'Vovich

Klimenko Petr Afanas'Evich

Kareva Elena Nikolaevna

Kappusheva Laura Magomedovna

Suknovalova Marija Vladimirovna

Kramarenko Marija Petrovna

Dates

2011-09-27Published

2010-01-27Filed