METHOD FOR PREDICTING SUCCESS OF IMPLANTATION IN THE STANDARD LONG PROTOCOL OF STIMULATION OF SUPEROVULATION Russian patent published in 2018 - IPC G01N33/68 

Abstract RU 2670450 C1

FIELD: medicine.

SUBSTANCE: invention relates to a method for predicting the results of in vitro fertilization and embryo transfer in a standard long protocol of stimulation of superovulation. Method consists in selecting peripheral blood in patients on day 21–23 of the menstrual cycle before stimulating superovulation and isolating the mononuclear fraction of blood cells. In cells of the mononuclear blood fraction, the content of the PIBF matrix RNA was determined by real-time PCR and at a level of matrix RNA PIBF more than 0.4 cu predict the success of in vitro fertilization and embryo transfer in the standard long protocol of stimulation of superovulation.

EFFECT: use of the invention provides increased availability and increased confidence in determining the probability of success of implantation in patients in a long IVF protocol.

1 cl, 1 tbl, 2 ex

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RU 2 670 450 C1

Authors

Saveleva Galina Mikhajlovna

Kareva Elena Nikolaevna

Shimanovskij Nikolaj Lvovich

Kappusheva Laura Magomedovna

Klimenko Mariya Petrovna

Kuvaeva Viktoriya Dmitrievna

Velichinskij Rodion Albertovich

Dates

2018-10-23Published

2017-12-25Filed