FIELD: medicine.
SUBSTANCE: invention refers to a mutant bacterium producing higher levels of intracellular and/or extracellular folate as compared with a wild type which is sensitive to methotrexate, and has growth rate at least 0,1 µ/hour when grown on a medium which contains methotrexate 1.25 mg/l and no folate-dependent metabolites. Also, the invention refers to a composition for foodstuff or food additive enrichment containing said bacterium, and to a method of sampling said bacteria.
EFFECT: invention allows producing high-folate bacteria.
13 cl, 3 dwg, 2 tbl
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