FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions concerns using live bacteria of nocardioform actinomycetes group for preparing a pharmaceutical composition and a method of using this composition. What is characterised is using nocardioform actinomycetes having an ability to survive in animal's macrophages; the live bacteria are attenuated by inactivating a gene, which codes a protein involved in destructing methylhexahydroindanedione propionate for preparing the pharmaceutical composition. The presented method for animal treatment for the purpose of protection against a disorder caused by infection by the bacterium of the nocardioform actinomycetes group, involves administering the pharmaceutical composition containing an effective amount of these bacteria into the animal.
EFFECT: presented inventions can be used for preventing the infections caused by nocardioform actinomycetes.
12 cl, 4 dwg, 11 tbl
