AZABICYCLO{3,1,0}HEXANE DERIVATIVES USED AS DOPAMINE RECEPTOR D3 MODULATORS Russian patent published in 2011 - IPC C07D403/12 C07D403/14 C07D405/14 C07D409/14 C07D413/14 C07D417/14 A61K31/403 A61P25/00 

Abstract RU 2434011 C2

FIELD: chemistry.

SUBSTANCE: described are novel derivatives of azabicyclo{3,1,0}hexane of general formula (I) or pharmaceutically acceptable salts thereof (values of radicals are given in the claim), synthesis method thereof, intermediate compounds, a pharmaceutical composition and use of the novel compounds in therapy as dopamine receptor D3 modulators, for example, for treating drug dependence or as antipsychotic agents.

EFFECT: improved properties of the derivatives.

34 cl, 122 ex

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Authors

Arista Luka

Bonanomi Dzhordzho

Kapelli Anna Marija

Damiani Federika

Di Fabio Romano

Dzhentile Gabriella

Khamprekht Diter Vol'Fgang

Mikeli Fabritsio

Tarsi Luka

Tedesko Dzhovanna

Terreni Sil'Vija

Dates

2011-11-20Published

2005-02-21Filed