EARLY DIAGNOSTIC TECHNIQUE FOR POSTRADIATION MYOCARDIAL DAMAGE IN PATIENTS WITH LUNG CANCER AT STAGES OF COMBINATION TREATMENT Russian patent published in 2012 - IPC A61B6/03 A61K49/06 A61N5/10 A61P35/00 A61B17/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, oncology and concerns early diagnosis of postradiation myocardial damage in patients suffering lung cancer at the stages of combination treatment by examining a morphofunctional myocardial status. It involves gated myocardial ^99mTc-MIBI SPECT described by two diagnostic criteria: myocardial perfusion values and left ventricular contractility. The criteria are evaluated fivefold: prior to treatment, after 2 courses of neoadjuvant chemotherapy and after 1, 6 and 12 months following a radical surgery with intraoperative radiation therapy. The derived values are compared with the reference values prior to treatment, and if observing a persistent decrease, postradiation myocardial damage is diagnosed.

EFFECT: technique provides adequate assessment of the progression myocardial status, higher diagnostic accuracy and reliability of early postradiation myocardial damages - up to one year prior to treatment in the given group of patients with lung of cancer having an initial considerable risk of development of a cardiac pathology.

1 ex, 1 app, 2 dwg