FIELD: medicine; cardiology; angiology; cardiac surgery; rehabilitation.
SUBSTANCE: invention can be used to predict the risk of progression of chronic heart failure with preserved ejection fraction (CHFPEF) in patients with non-obstructive atherosclerosis of the coronary arteries during 12 months of observation. In patients immediately after the diagnosis of CHFPEF, the serum level of the N-terminal fragment of brain natriuretic hormone (B-type) (NT-proBNP) is determined using an enzyme-linked immunosorbent assay and the value of myocardial blood flow reserve (MFR) using dynamic single-photon emission tomography of the myocardium. If the NT-proBNP level is 760.5 pg/mL or more and MFR is 1.62 or less, a high risk of progression of CHFPEF is predicted.
EFFECT: method provides the ability to improve the quality of predicting the risk of progression of CHFPEF in patients with non-obstructive atherosclerosis of the coronary arteries during 12 months of observation by determining the content of NT-proBNP in the blood serum and the value of myocardial blood flow reserve MFR.
1 cl, 1 dwg, 1 tbl, 2 ex
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