FIELD: medicine.
SUBSTANCE: method includes preparation of platelets concentrates (PC) and the irradiation with ultraviolet radiation with the wavelength from 200 nm to 280 nm (UV-C radiation) with radiation energy in the range from 0.01 to 2 J/cm2. Every dose of PC is contained in flexible, UV-permeable flat package for irradiation with the volume up to 5000 ml, filled by less than 30% of maximal capacity. The package during irradiation is moved by the way of shaking, rocking, rotating, so that content is circulating and during circulation the zones with variable thickness of layers is formed. Additionally the irradiation with UV-B radiation with radiation energy in the range from 0.3 to 5 J/cm2 is performed. The plasma content in PC is more than 20% w/w.
EFFECT: pathogenic microbes and leucocytes deactivation while the platelet function remains unaltered.
25 cl, 8 tbl, 8 ex
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Authors
Dates
2012-02-10—Published
2006-12-21—Filed