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RU

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2 443 710

(13)

C1

(51)

IPC

C07K7/64(2006-01-01)

A61K38/12(2006-01-01)

A61P7/10(2006-01-01)

(21) (22)

Application

2010141917/04, 2010-10-13

(24)

Start date

2010-10-13

(22)

Actual filing date

2010-10-13

(45)

Published

2012-02-27

(72)

Inventor

Shirinskij Vladimir PavlovichStepanova Elena OlegovnaSidorova Marija VladimirovnaSekridova Aleksandra VladimirovnaBespalova Zhanna DmitrievnaAz'Muko Andrej Andreevich

(73)

Holder

Federal'Noe Gosudarstvennoe Uchrezhdenie Kardiologicheskij Nauchno-Proizvodstvennyj Kompleks" Ministerstva Zdravookhranenija I Sotsial'Nogo Razvitija Rossijskoj Federatsii Minzdravsotsrazvitija Rossii)Rossijskaja Federatsija V Litse Ministerstva Obrazovanija I Nauki Rossijskoj Federatsii Rossii)

CYCLIC NONAPEPTIDE SHOWING ABILITY TO INHIBIT MYOSIN LIGHT CHAIN KINASE Russian patent published in 2012 - IPC C07K7/64 A61K38/12 A61P7/10 

Abstract RU 2443710 C1

FIELD: medicine.

SUBSTANCE: invention refers to biologically active peptides able to inhibit myosin light chain kinase and thereby regulate the variability of vascular endothelial permeability. What is offered is a cyclic nonapeptide of formula cyclo[-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-].

EFFECT: peptide can find application as a decongestant in various fields of medicine.

2 dwg, 2 ex

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RU 2 443 710 C1

Authors

Shirinskij Vladimir Pavlovich

Stepanova Elena Olegovna

Sidorova Marija Vladimirovna

Sekridova Aleksandra Vladimirovna

Bespalova Zhanna Dmitrievna

Az'Muko Andrej Andreevich

Dates

2012-02-27—Published

2010-10-13—Filed

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