PROTEOLYTICALLY STABLE NONAPEPTIDE CAPABLE OF PREVENTING AN INCREASE IN HYPERPERMEABILITY OF VASCULAR ENDOTHELIUM Russian patent published in 2019 - IPC C07K7/06 A61K38/08 A61P7/10 

Abstract RU 2682878 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a low-toxic, proteolytically stable, biologically active nonapeptide of formula H-Lys-D-Lys-Arg-Ala-Ala-Arg-Ala-Thr-Ser-NH2 (l). Claimed peptide can be used in medicine as a decongestant.

EFFECT: claimed peptide is able to prevent the development of vascular hyperpermeability in stressful situations.

1 cl, 4 dwg, 3 tbl, 5 ex

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RU 2 682 878 C1

Authors

Arzamastsev Evgenij Veniaminovich

Azmuko Andrej Andreevich

Bushuev Valerij Nikolaevich

Kazakova Olga Alekseevna

Molokoedov Aleksandr Sergeevich

Ovchinnikov Mikhail Vladimirovich

Palkeeva Marina Evgenevna

Sidorova Mariya Vladimirovna

Samsonov Mikhail Vasilevich

Terekhova Olga Aleksandrovna

Khapchaev Asker Yusufovich

Shirinskij Vladimir Pavlovich

Dates

2019-03-22Published

2018-09-26Filed