METHOD OF QUANTITATIVE ESTIMATION OF ORGANOTYPIC CHANGE OF PATHOLOGIC NIDUS IN TREATMENT OF PATIENTS WITH DEFECT-PSEUDOARTHROSES OF DIAPHYSIS OF LONG BONES Russian patent published in 2012 - IPC A61B6/03 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, orthopedics, radiodiagnostics. In patients with defect-pseudoarthroses of diaphysis of long bones at stages of treatment performed are sessions of computer tomography simultaneously of paired segments of patient's extremities at the level of pathologic nidus, storing images in IBM-compatible format. Single-level scans, transferred into gray palette are analysed, calibrated by standard segment and in the image of healthy segment range and maximal value of intensity of soft tissues (I_max) are determined. From all selected for analysis images, pixels with intensity lower than I_max+1 are deleted, replacing them with black. By flooding with red colour image of soft tissue area, non-closed spaces in area of shadows of bone structures are visualised, leaving black bounded by bone walls shadows of bone-marrow cavities, black colour is replaced by blue. Processed images arew segmented, separating all gray pixels - shadows of bone structures into one file, blue shadows of bone-marrow cavities - in another, storing them pixel by pixel in form of tables. Areas of shadows of bone structures (A_b), bone-marrow cavities (A_m) and index of organotypicaslness by their ratio -A_b/A_m are calculated.

EFFECT: method ensures quantitative estimation of dynamics of changes of bone-marrow cavities and their bone walls ratio in zone of pathologic nidus as index of organotypical change in process of treatment of patients with defect-pseiudoarthroses of diaphysis of long bones.

2 cl, 6 dwg