METHOD FOR KERATOPROSTHESIS OF VASCULAR COMPLICATED LEUKOMAS WITH USING BIOKERATOPROSTHETIC COMPLEX Russian patent published in 2012 - IPC A61F9/07 

Abstract RU 2444340 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to ophthalmology, and can be used for treating complicated leukomas. A recess matched with a support plate of a keratoprosthesis (SPK) is formed in a stroma of an allogenic donor cornea. The recess cornea is treated with riboflavin and exposed UV light to improve its strength properties and resistance to lachrymal proteolytic enzyme. Before the SPK is introduced in the formed recess, autofibroblasts pre-recovered from recipient's skin are cultured in a monolayer on the SPK's surface; then the prepared SPK and said autofibroblasts cultured on collagenic microcarriers are introduced in the formed recess that promotes to form a connective tissue matrix surrounding the SPK, and after the SPK has been fastened to leukoma tissues, it is coated with an amniotic membrane to prevent the grafts from drying.

EFFECT: more effective and safe method.

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RU 2 444 340 C1

Authors

Takhchidi Khristo Periklovich

Borzenok Sergej Anatol'Evich

Maljugin Boris Ehduardovich

Vasil'Ev Andrej Valentinovich

Shipunova Anna Vladimirovna

Dashinimaev Ehrdehm Bairovich

Moroz Zinaida Ivanovna

Kovshun Evgenija Vladimirovna

Komakh Jurij Alekseevich

Volkova Ol'Ga Sergeevna

Dates

2012-03-10Published

2010-09-15Filed