METHOD FOR PRODUCING CARRIER OF BIOLOGICALLY ACTIVE COMPOUNDS OF INTERPOLYELECTROLYTE COMPLEX Russian patent published in 2012 - IPC A61K47/34 C08G81/02 A61K9/22 

Abstract RU 2445118 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutics, and concerns a method for producing a carrier for biologically active compounds of an interpolyelectrolyte complex by mixing copolymer of a cationic nature of dimethylaminoethylmetacrylate, butylmetacrylate and methylmetacrylate in proportions 2:1:1 reduced to pH 2.0-7.0 and gel of lightly crosslinked polyacrylic acid with pH 2.0-7.0; as a solvent, water is used with both solutions have the equal pre-mixing pH values; for copolymer of dimethylaminoethylmetacrylate and neutral methacrylic esters, and for crosslinked polyacrylic acid, acetic acid 0.1 M and sodium hydroxide 0.1 M taken in certain proportions, and recovering the end product.

EFFECT: ensured improvement of the pharmaceutical characteristics and creation of the release profile of various drug preparations.

4 cl, 4 dwg, 2 tbl, 4 ex

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RU 2 445 118 C2

Authors

Mustafin Ruslan Ibragimovich

Kabanova Tat'Jana Vladimirovna

Bukhovets Aleksandra Viktorovna

Garipova Venera Rasimovna

Nasibullin Shamil' Fljurovich

Dates

2012-03-20Published

2009-12-22Filed