PERORAL SYSTEM OF MEDICATION DELIVERY INTO INTESTINE REGION Russian patent published in 2012 - IPC A61K47/30 A61K31/196 A61K31/405 

Abstract RU 2467766 C1

FIELD: medicine.

SUBSTANCE: invention relates to system of peroral delivery of medications with controlled release into intestine region, which includes therapeutically active component, selected from sodium diclofenac, oxprenolol, methoprolol, nifedipine, indomethacin, ibuprofen, isosorbide, theophylline and pharmaceutically acceptable carrier. As pharmaceutically acceptable carrier the system contains polymer carrier based on interpolyelectrolyte complex, obtained by interaction of cross-linked polyacrylic acid (polyanion) with dimethylaminoethyl methacrylate copolymer and neutral esters of methacrylic acid (polycation).

EFFECT: invention ensures controlled release along entire intestine, dose reduction and prolonged action of active component.

4 cl, 4 dwg, 3 tbl, 5 ex

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RU 2 467 766 C1

Authors

Mustafin Ruslan Ibragimovich

Semina Irina Ivanovna

Bukhovets Aleksandra Viktorovna

Garipova Venera Rasimovna

Sitenkov Aleksandr Jur'Evich

Kabanova Tat'Jana Vladimirovna

Dates

2012-11-27Published

2011-05-10Filed