HETEROCYCLIC COMPOUNDS HAVING AFFINITY TO MUSCARINE RECEPTORS Russian patent published in 2012 - IPC C07D401/04 C07D413/04 C07D401/14 C07D405/14 C07D453/02 C07D451/02 A61K31/4439 A61K31/4427 A61K31/439 A61K31/46 A61P25/28 

Abstract RU 2446166 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to heterocyclic compounds of formula ,

wherein X2 represents residue C-Z-R2 or C-R3, wherein Z represents NH or S; R1 is selected from structures , and R2 and R3 have the values specified in cl.1 of the patent claim, or to their pharmaceutically acceptable salts. The invention also refers to a pharmaceutical composition, a series of specific compounds, application of the declared compounds and to an intermediate compound for preparing the compounds of formula (I).

EFFECT: compounds under the invention have affinity to muscarine receptors and can be used in treating, relieving and preventing diseases and conditions mediated by muscarine receptors.

13 cl, 3 tbl

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RU 2 446 166 C2

Authors

Stojt Aksel

Kolen Khejn K.A.S.

Krjuse Kornelis G.

Rejnders Jan Kh.

Dates

2012-03-27Published

2008-04-23Filed