FIELD: pharmacology.
SUBSTANCE: subject of the invention is pyrazolo [3,4-c] pyridines of the formula I
,
including their stereoisomers, geometric isomers, tautomers and pharmaceutically acceptable salts, wherein R1 and R2 have the values disclosed in the claims. These compounds are useful for inhibiting Pim-kinases and for treating disorders such as cancer, mediated by Pim-kinase. Methods for using compounds of formula I for in vitro, in situ and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells or related pathological conditions are disclosed.
EFFECT: increased application effeciency.
4 cl, 3 tbl, 328 ex
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