RADIOPHARMACEUTICAL PRODUCTS Russian patent published in 2012 - IPC A61K51/00 A61K51/12 G21F5/15 G21F5/12 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to product agent of visualisation, which includes radiopharmaceutical composition, supplied in hermetic container. Said radiopharmaceutical composition contains radioisotope, suitable for medical visualisation, presented in biocompatible carrier, in form, suitable for introduction to mammal. Said hermetic container is provided with closure, suitable for puncturing with needle for subcutaneous injections, preserving at the same time seal integrity, and said closure is covered with coating, which includes copolymer of ethylene and tetrafluorethylene (ETFE), on those of its surfaces, which are in contact with container content. Invention also relates to set for preparation of product agent of visualisation, which includes mentioned above hermetic container, which contains non-radioactive precursor, containing reactionable substituent, able to interact with radioisotope source with formation of said pharmaceutical composition. Invention also relates to method of obtaining product agent of visualisation, which includes interaction of precursor mentioned above with radioisotope source in hermetic container.

EFFECT: invention ensures reduction of admixtures in radiopharmaceutical composition due to covering closure with copolymer of ethylene and tetrafluorethylene.

28 cl, 3 tbl, 2 dwg, 6 ex