METHOD OF VERIFYING DIAGNOSIS OF PHEOCHROMOCYTOMA AND/OR PARAGANGLIOMA IN PATIENTS WITH EARLIER DETECTED LEVEL OF DAILY CONJUGATED METANEPHRINE AND/OR CONJUGATED NORMETANEPHRINE EXCRETION, EXCEEDING UPPER NORM LIMIT Russian patent published in 2012 - IPC G01N33/53 

Abstract RU 2449288 C1

FIELD: medicine.

SUBSTANCE: in patients with earlier detected excess of upper norm limit of level of daily conjugated metanephrine and/or conjugated normetanephrine excretion level of daily excretion of conjugated metanephrine and/or conjugated normetanephrine is determined in sample of collected urine at the background of clonidine intake. Sample is positive if the level of daily excretion of conjugated normetanephrine and/or conjugated metanephrine in sample of collected urine is higher than upper norm limit. Claimed method of diagnosis verification possesses high sensitivity and specificity.

EFFECT: method application makes it possible to avoid carrying out unjustified surgery in patients with essential arterial hypertension and hormonally non-active formation of adrenal gland.

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RU 2 449 288 C1

Authors

Dedov Ivan Ivanovich

Mel'Nichenko Galina Afanas'Evna

Troshina Ekaterina Anatol'Evna

Bel'Tsevich Dmitrij Germanovich

Jukina Marina Jur'Evna

Kuznetsov Nikolaj Sergeevich

Vanushko Vladimir Ehduardovich

Lysenko Mar'Jana Anatol'Evna

Il'In Aleksandr Viktorovich

Dates

2012-04-27Published

2011-01-13Filed