FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to therapy, angiosurgery and cardiology. In a patient with resistant arterial hypertension, determine the parameters of daily monitoring of arterial pressure, the variability of systolic blood pressure during the day, the level of systolic blood pressure at night, the "load" of increased systolic blood pressure at night, as well as the concentration of tissue inhibitor of matrix metalloproteinases of type 1 in venous blood and the content of normetanephrine in daily urine. Based on the data obtained, the prognosis of the effectiveness of renal denervation (Y) is determined. At Y < 0.5, predict a lack of effect and consider the carrying out of renal denervation not shown. With a value of Y ≥ 0.5 predict the presence of the effect and consider carrying out the renal denervation shown.
EFFECT: method allows to increase the accuracy of the prognosis for the antihypertensive efficacy of sympathetic renal denervation, which reduces the unreasonable risk of complications associated with this procedure in patients with a low probability of an effective response, as well as the cost of an expensive procedure.
1 cl, 2 ex
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Authors
Dates
2018-06-21—Published
2017-06-26—Filed