FIELD: medicine; pharmaceutics.
SUBSTANCE: invention relates to pyridinone derivatives of formula I or a pharmaceutically acceptable salt thereof and pharmaceutical compositions based thereon, having cell killing activity, activated by small molecules (SMACK), and having activity for selective destruction of HIV-infected cells expressing GAG-POL.
EFFECT: using the invention enables treating HIV infections, as well as treating and preventing or delaying the onset or progression of AIDS or AIDS-associated complex (ARC).
16 cl, 16 tbl, 43 ex
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