FIELD: chemistry.
SUBSTANCE: invention relates to compounds of formula (I): 
(I), in which: A is a linear or a branched (C1-C6)alkyl group, a linear or a branched (C1-C6)alkoxy group, a -S-(C1-C6)alkyl group, a linear or a branched (C1-C6)polyhalogen-alkyl group, a hydroxy group, a cyano group or a halogen atom; R1, R2, R3, R4 and R5 independently denote a hydrogen atom, a halogen atom, a linear or a branched (C1-C6)alkyl group, a linear or a branched (C2-C6)alkenyl group, a linear or a branched (C2-C6)alkynyl group, a linear or a branched (C1-C6)polyhalogen-alkyl group, a hydroxy group, a linear or a branched (C1-C6)alkoxy group, a -S-(C1-C6)alkyl group, a nitro group, -alkyl(C0-C6)-NR8R8′, -O-Cy1, -alkyl(C0-C6)-Cy1, -alkenyl(C2-C6)-Cy1, -alkynyl(C2-C6)-Cy1, -O-alkyl(C1-C6)-R9, -C(O)-OR8, -O-C(O)-R8, -NR8-C(O)-R8′, -NR8-C(O)-OR8′, -alkyl(C1-C6)-NR8-C(O)R8′; X represents a carbon or a nitrogen atom; R6 represents hydrogen, a linear or a branched (C1-C8)alkyl group, an aryl group, heteroaryl-alkyl(C1-C6); R7 is a linear or a branched (C1-C6)alkyl group, a linear or a branched (C2-C6)alkenyl group, a linear or a branched (C2-C6)alkynyl group, -Cy3, -alkynyl(C2-C6)-Cy3,-Cy3-Cy4, -alkynyl(C2-C6)-O-Cy3, -Cy3-alkyl(C0-C6)-O-alkyl(C0-C6)-Cy4, a halogen atom, a cyano group, -C(O)-R11, -C(O)-NR11R11′, values of other radicals are defined in cl.1 of the formula.
EFFECT: compounds can be used as pro-apoptotic agents.
50 cl, 2 tbl, 871 ex
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