FIELD: chemistry.
SUBSTANCE: described is a method of producing 6-(3-phenoxyphenyl-substituted) 2,4-diamino-simm-triazines of formula where X=single bond, -CH=CH-; -CH2-CH2-; -CH2-; CH2-NH-CH2-CH2-; -CH2-O-CH2-CH2-, involving reaction of corresponding nitriles with dicyandiamide in the presence of potassium hydroxide in dimethyl formamide at temperature 130-135°C and molar ratio of nitrile to dicyandiamide equal to 1:1.2.
EFFECT: method ensures high output and high degree of purity of the end product, which can be used as a semi-product in synthesis of biologically active substances.
1 cl, 8 ex
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Authors
Dates
2012-05-27—Published
2011-04-01—Filed