FIELD: chemistry.
SUBSTANCE: invention relates to chemistry and specifically to a method of producing 3-phenoxyphenylacetonitrile of formula which can be used as synthon in synthesis of biologically active substances. The method involves reaction of 3-phenoxybenzylchloride with acetone cyanohydrin in the presence of sodium hydroxide and dimethyl formamide.
EFFECT: method enables to obtain 3-phenoxyphenylacetonitrile using a simpler and easily producible method with good output and high degree of purity.
2 ex
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Authors
Dates
2012-05-27—Published
2011-02-14—Filed