5-HYDROXYMETHYLOXAZOLIDIN-2-ONE DERIVATIVES Russian patent published in 2012 - IPC C07D413/14 C07D471/04 A61K31/4545 A61K31/4709 A61K31/661 A61P31/04 

FIELD: chemistry.

SUBSTANCE: invention relates to compounds of general formula , where R¹ denotes OH, OPO₃H₂ or OCOR⁵; R² denotes H, OH or OPO₃H₂; A denotes N or CR⁶; R³ denotes fluorine; R⁴ denotes H, C_1-3alkyl or C_3-6cycloalkyl; R⁵ denotes an alanine residue; R⁶ denotes H, C_1-6alkoxy group or halogen; and n=0 or 1; and to pharmaceutically acceptable salts of compounds of formula I. The invention also relates to a pharmaceutical composition having antibacterial activity, and to use of compounds of formula I to obtain a medicinal agent for preventing or treating bacterial infections.

EFFECT: compounds of formula I, having antibacterial activity.

14 cl, 3 dwg, 2 tbl, 14 ex