ANTIBIOTIC DERIVATIVES OF 2-OXO-OXAZOLIDINE-3, 5-DIYL Russian patent published in 2017 - IPC C07D417/14 C07D471/04 C07D498/04 C07D513/04 C07D513/14 A61K31/5383 A61K31/5415 A61K31/542 A61P31/04 

FIELD: pharmaceutics.

SUBSTANCE: invention relates to compounds of formula I or pharmaceutically acceptable salts possessing antibacterial action,

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wherein R^1a represents H or carboxy and R^1b represents H, or R^1a and R^1b represent together or group *-C(O)-NH-S-^# or group *-C(OH)=N-S-^# in which "*" is connection point of R^1a and "^#" is connection point of R^1b; R² represents H, (C₁-C₃)alkyl, hydroxy-(C₁-C₃)alkyl, benzyl or (C₃-C₅)cycloalkyl; R³ represents H or halogen; U is N or CR⁴; wherein R⁴ represents H or (C₁-C₃)alkoxy; A represents CH, B represents NH and m is 1 or 2 and n is 1 or 2; or A is N, B is absent, m is 2 and n is 2; Y represents CH or N; and Q represents O or S. Invention also relates to pharmaceutical composition.

EFFECT: novel compounds are obtained, which can be used for preventing or treating bacterial infections.

15 cl, 25 ex