FIELD: medicine.
SUBSTANCE: method provides DNA recovery of an analysed plague agent strain that is followed by conducting a PCR with the use of oligonucleotide primers for streptomycin, chloramphenicol and kanamycin resistance genes - strA, strB, cat and npt (nucleotide sequences of the primers are presented in the description). The antibiotic-resistance genes are detected by the presence of the amplified fragments of the strA, strB, cat and npt genes having the sizes of 387, 705, 377 and 361 base pairs respectively.
EFFECT: using the invention provides effective and reliable detection of the antibiotic-resistance genes in plague agent strains.
4 ex
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